Sunday, December 15, 2013

Glioblastoma Research & The Idea Of Gene Changes

By Rob Sutter


If you have been involved in glioblastoma research in some way or another, you know all about the condition at hand. Gliomas are viewed as some of the most common, not to mention most severe, tumors seen in the brain and this is why research seems to focus on them in particular. That being said, what can be done in order to help the matter that much more? After reading up on the matter, it seems like there may be a new relation of sorts.

An article on BioNews Texas spoke about how there were a number of new findings related to glioblastoma multiforme, which is something that researchers have focused on and for good reasons. The report said that, in 2013, there are about 23,000 cases of this condition being expected and most patients pass away within 15 months of diagnosis. As you can imagine, there has been work done in order to make better sense of this condition. What has come to the surface as a result of such efforts?

Professor as well as the chair of the Cancer Genome Atlas, Lynda Chin, M.D., spoke about the findings that came about following a sojourn of five years. There has been quite a bit of data that has been uncovered and I think that there are many ways it could be put into practice. Such information has been able to detail such things as genetic mutations, deletions, and what have you. I think that, if such knowledge is put into effect, more effective therapies stand a strong chance of coming about.

I believe that past mutations have to be looked to as well, a point that is supported by organizations along the lines of Voices against Brain Cancer. Keep in mind that there are many individuals who have been involved in the realm of glioblastoma research and they can tell you about the many findings related to genes. The report said that 61 mutated genes have been newly discovered and one of the more interesting points of information had to do with the epidermal growth factor receptor. For those who do not know, the EGFR gene was seen as mutated in 57% of these tumors.

When you are looking at glioblastoma research, you want to see what exactly is changed in the growths in question. Those who have spent ample time looking into this profession can tell you that it is one of the most intricate fields that you can imagine, so much background information being seen. However, it is worth noting that there are many genes which might have been changed thanks to the condition. The ability to understand this can only make way for greater therapies for the sake of potential remedies later on.




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