Sunday, January 12, 2014

Brain Cancer & Referring To The P1D1 Gene

By Rob Sutter

What is it that can be said about the P1D1 gene as far as brain cancer, in general, is concerned? This particular gene entails the signaling of insulin and mitochondrial function within the brain alike, meaning that it is an integral aspect that not many people are familiar with. For the longest time, it seems like this gene has only been focused on when it came to conditions like obesity and diabetes. However, it seems like this type of cancer will be one to take into account as well.

I do not think that it is totally surprising to see how this gene can play into brain cancer efforts in the long term. After all, therapies have been put together in the past and it's not uncommon for them to utilize certain aspects that might have been linked to conditions outside of this one. However, when considering that there is a chance for them to come into play here, it's an idea that can draw the attention of organizations along the lines of Voices against Brain Cancer. What is it that can be said about the integral nature of P1D1, though?

An article on Business Wire went into detail about how the level of messenger RNA of the gene known as P1D1 could possibly be linked to clinical outcomes. In particular, these focused on medulloblastomas and gliomas, the latter of which being more aggressive and prevalent by comparison. As it seems, P1D1 actually inhibits cell growth when it comes to these conditions. Reports were analyzed, not only in terms of adults with these conditions but children who have had them since they were young as well.

With the results of the therapy brought to the forefront, greater levels of P1D1 mRNA have been connected to the increases in survival rates of patients. The way that P1D1 works is when seen in high doses can actually work in order to kill tumor cells and stop the proliferation of the cells as well. With many adults studied, according to the article, each of them was able to see better survival rates than they would have had otherwise. It is clear that the presence of this gene is an idea that calls for attention.

These types of therapies are done consistently and I do not think that anyone can speak against the levels of potential that they possess. To me, they are able to address this condition, which has normally been viewed as one of the most serious in the human body. While conventional surgery on its own exists, results are most likely going to vary when looking at a collective group of patients. Perhaps this is one of the reasons why looking more into the P1D1 gene is for the best.

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